Argon plasma coagulation for the treatment of chronic radiation proctitis – real-world data from Indonesian National Cancer Center

Authors

  • Lianda Siregar Department of Gastroentero-hepatology, Dharmais Hospital, Indonesian National Cancer Center, Jakarta
  • Imelda Maria Loho Department of Gastroentero-hepatology, Dharmais Hospital, Indonesian National Cancer Center, Jakarta
  • Agus Sudiro Waspodo Department of Gastroentero-hepatology, Dharmais Hospital, Indonesian National Cancer Center, Jakarta
  • Rahmanandhika Swadari Department of Gastroentero-hepatology, Dharmais Hospital, Indonesian National Cancer Center, Jakarta
  • Benedicta Audrey Maharani Department of Gastroentero-hepatology, Dharmais Hospital, Indonesian National Cancer Center, Jakarta

DOI:

https://doi.org/10.24871/2222021106-109

Keywords:

Argon plasma coagulation, chronic radiation proctitis, treatment, endoscopy

Abstract

Background: This study aimed to evaluate the endoscopic features and clinical outcome of patients with chronic radiation proctitis (CRP) at one year after argon plasma coagulation (APC) treatment. 

Method: Between March 2016 and September 2019, a total of 48 female patients with CRP were treated with APC and their medical records were retrospectively reviewed. APC treatment was done every 3 to 54 weeks, with a median of 8 weeks. Number of APC was decided by the treating physician according to the severity of illness. Endoscopic and clinical features at one year after the final APC were recorded as the effectiveness of APC.

Results: Of 48 patients, 26 patients were included in this study. Number of APC sessions varied between 1 to 5 sessions of APC for each patient. Of 26 patients, 22 patients achieved clinical improvement and four patients did not achieve clinical improvement at one year after the last APC session. Of the four patients who failed to achieve clinical improvement, two patients underwent surgery, one patient had occasional mild rectal bleeding, and one patient required regular transfusion. Of 22 patients with clinical improvement at one-year after the last APC, improvement of endoscopic features was found in 20 patients. Of four patients who did not achieve endoscopic improvement, diagnostic colonoscopy showed telangiectasis of more than 50% of rectal surface in 1 patient, presence of blood in 2 patients, and presence of ulceration of < 1 cm in 1 patient.

Conclusion: APC is an effective treatment option for CRP.

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Published

2021-09-27

How to Cite

Siregar, L., Loho, I. M., Waspodo, A. S., Swadari, R., & Maharani, B. A. (2021). Argon plasma coagulation for the treatment of chronic radiation proctitis – real-world data from Indonesian National Cancer Center. The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy, 22(2), 106–109. https://doi.org/10.24871/2222021106-109

Issue

Vol. 22 No. 2 (2021): VOLUME 22, NUMBER 2, August 2021

Section

Original Articles

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