Gastrointestinal Amyloidosis: Diagnostic Approach and Treatment

Authors

  • Catarina Budyono Department of Internal Medicine, Faculty of Medicine, University of Indonesia/Dr. Cipto Mangunkusumo General National Hospital, Jakarta
  • Achmad Fauzi Division of Gastroenterology, Department of Internal Medicine, Faculty of Medicine/Dr. Cipto Mangunkusumo General National Hospital, Jakarta
  • Dadang Makmun Division of Gastroenterology, Department of Internal Medicine, Faculty of Medicine/Dr. Cipto Mangunkusumo General National Hospital, Jakarta

DOI:

https://doi.org/10.24871/1632015172-178

Keywords:

amyloidosis, diagnostic, treatment

Abstract

Amyloidosis is a disease marked by deposition of misfolded proteins, known as amyloids, in the extracellular space, including gastrointestinal tract. According to the precursor protein, amyloidosis is classified into six types; all of which can be involved in the gastrointestinal tract. Amyloidosis has weight loss and gastrointestinal bleeding as the most frequent symptoms. Gastrointestinal tract biopsy is diagnostic in most cases of amyloidosis and Congo red stain is used to confirm the amyloid proteins deposit. Treatment of amyloidosis consists of controlling symptoms, terminating protein formation and deposit, and treating the underlying diseases. Chemotherapy might be applied depends on the type of amyloidosis. 

Downloads

Published

2015-12-01

How to Cite

Budyono, C., Fauzi, A., & Makmun, D. (2015). Gastrointestinal Amyloidosis: Diagnostic Approach and Treatment. The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy, 16(3), 172–178. https://doi.org/10.24871/1632015172-178

Issue

Vol. 16 No. 3 (2015): VOLUME 16, NUMBER 3, December 2015

Section

Review Article

License

Authors who publish with this journal agree to the following terms:

a. Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.

b. Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.

c. Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).