Immunocompetent Expression of CD4+ T Cell and CD8+ T Cell, TNF-alpha and INF-gamma in Patient with Chronic Hepatitis C

Authors

  • Ellyza Nasrul

DOI:

https://doi.org/10.24871/72200633-37

Abstract

Aim: To investigate the expression CD4+ T cell and CD8+ T cell as well as TNF-a and INF-g level on chronic hepatitis C.
Methods: This is a cross-sectional study. Forty patients with chronic hepatitis C based on laboratory examination, who were collected from blood transfusion centers at Dr. M. Djamil Hospital. The control group used forty healthy samples.
Results: There were 40 chronic hepatitis C cases satisfying the inclusion criteria. We found that CD4+ T cells count 50.35 ± 3.18%; CD8+ T cells count 59.37 ± 3.52%; TNF-a level 22.03 ± 3.72 pg/ml and INF-g level 4.47 ± 1.47 pg/ml.
Conclusion: The chronic infection hepatitis C virus have given the effects on the immunocompetent cells which increased of CD4+, CD8+, TNF-a level and INF-g level.
Keywords: hepatitis C virus, CD4+ T cell, CD8+ T cell, cytokines TNF-a, INF-g
VOLUME 7, ISSUE 2, August 2006

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Published

2006-01-08

How to Cite

Nasrul, E. (2006). Immunocompetent Expression of CD4+ T Cell and CD8+ T Cell, TNF-alpha and INF-gamma in Patient with Chronic Hepatitis C. The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy, 7(2), 33–37. https://doi.org/10.24871/72200633-37

Issue

VOLUME 7, ISSUE 2, August 2006

Section

Original Articles

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