Treatment of Chronic Hepatitis B

Authors

  • Prasna Pramita
  • Rino A Gani
  • Ali Sulaiman

DOI:

https://doi.org/10.24871/6120059-15

Abstract

Chronic hepatitis B is still a major health problem in Indonesia. Unfortunately, to date, treatment of chronic HBV (Hepatitis B virus) infection had not shown satisfactory
Result. Monotherapy with alpha interferon or lamivudine have been widely used as treatment of chronic HBV. However, treatment response to Alpha interferon in Asian people was not satisfactory (15% - 20%), while monotherapy with lamivudine was not sufficient to eradicate HBV in chronically infected patients and commonly induce drug resistance. The occurrence of chronic hepatitis B resistant to lamivudine had encouraged development of newer agents such as adefovir, entecavir, emtricitabine and nucleoside analog. New therapeutic strategy using combination therapy should be considered if there is no sufficient response to monotherapy.
Keywords: Treatment, chronic hepatitis B, combination therapy
VOLUME 6, ISSUE 1, April 2005

Downloads

Published

2005-01-04

How to Cite

Pramita, P., Gani, R. A., & Sulaiman, A. (2005). Treatment of Chronic Hepatitis B. The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy, 6(1), 9–15. https://doi.org/10.24871/6120059-15

Issue

VOLUME 6, ISSUE 1, April 2005

Section

Review Article

License

Authors who publish with this journal agree to the following terms:

a. Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.

b. Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.

c. Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).